中国血液净化

中国血液净化 ›› 2016, Vol. 15 ›› Issue (10): 513-516.doi: 10.3969/j.issn.1671-4091.2016.10.001

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糖尿病患者腹膜透析治疗的研究进展

阳晓1,余学清1   

  1. 广州市,中山大学附属第一医院肾内科
  • 收稿日期:2016-05-30 修回日期:2016-06-05 出版日期:2016-10-12 发布日期:2016-10-10
  • 通讯作者: 阳 E-mail:yangxsysu@126.com
  • 基金资助:

    广州市科技计划项目(2014Y2-00102)，国家自然科学基金(81570614)，广东省自然科学基金(2014A030313139)

Peritoneal dialysis for diabetic patients with end-stage renal disease

  • Received:2016-05-30 Revised:2016-06-05 Online:2016-10-12 Published:2016-10-10

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摘要： 糖尿病是导致终末期肾脏病（End stage renal disease,ESRD）的主要病因。因其较高的合并症和并发症，糖尿病ESRD 患者透析治疗生存率低于非糖尿病患者。关于糖尿病ESRD 患者透析时机及透析方式选择目前尚无定论。腹膜透析治疗糖尿病ESRD 患者具有一定优势，但也存在其局限性。本文重点阐述了糖尿病ESRD 腹膜透析患者的管理策略，如维持液体平衡、积极控制血糖、重视残肾和腹膜功能保护以及降低心血管疾病风险等，旨在改善患者的长期预后。

关键词: 糖尿病, 终末期肾病, 腹膜透析, 临床结局

Abstract: Diabetes mellitus (DM) is the leading cause of end-stage renal disease (ESRD) in many countries. Most diabetic patients with ESRD are maintained on renal replacement therapy. Compared with patients without diabetes, patients with diabetes on dialysis generally have poorer survival rates because of a higher incidence of complications and comorbidities.The question on timing of start of dialysis and optimal first choice of dialysis modality in diabetes mellitus patients remains a matter of debate. Peritoneal dialysis (PD) offers multiple benefits for the treatment of ESRD patients with diabetes, however PD is also associated
with certain negative factors inherent to the use of this modality. The present review addresses the strategies for the care of diabetic PD patients.With improved fluid balance, better glycemic control, optimal preservation of residual renal function and peritoneal function as well as the reducing risk factors of cardiovascular disease, there is hope for improving the long-term outcomes of diabetic PD patients.

Key words: Diabetes mellitus, End-stage renal disease, Peritoneal dialysis, Clinical outcomes