Chinese Journal of Blood Purification

12 May 2020, Volume 19 Issue 05 Previous Issue    Next Issue

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The correlation analysis between serum sclerostin and vascular calcification in uremia patients 2020, 19 (05):  289-293.  doi: 10.3969/j.issn.1671-4091.2020.05.001 Abstract ( 390 )   PDF (425KB) ( 756 )   【Abstract】Objective To observe the correlation between vascular calcification (VC) and serum sclerostin level in uremia patients. Method Serum sclerostin levels were detected by ELISA in 56 patients who underwent arteriovenous fistula operation (AVF group), 56 maintenance hemodialysis patients (MHD group), and 56 normal individuals (control group). Their demographic data and biochemical indicators were collected. Abdominal CT was used to evaluate abdominal aortic calcification. Hematoxylin-eosin (HE) staining and alizarin red staining were used to examine the calcification of the radial artery in surgical samples. Result VC rate (F=29.973, P＜0.001), serum phosphorus (F=45.308, P＜0.001), magnesium (F=42.468, P＜0.001), uric acid (F=16.049, P＜0.001), alkaline phosphatase (F=5.677, P=0.005), triglyceride (F=5.521, P=0.005),immunoreactive parathyroid hormone(F=22.001, P＜0.001) and serum sclerostin(F=202.458, P＜0.001) were significantly higher in AVF and MHD groups than in control group. Serum calcium(F=15.006,P＜0.001) and 25-OH-vitamin D (F=9.904, P=0.000) were lower in AVF and MHD groups than in control group. In AVF group, patients with radial artery calcification had older age (t=2.033, P=0.048), and higher serum phosphorus (t=4.170,P＜0.001), immunoreactive parathyroid hormone (t=-2.374, P=0.018) and serum sclerostin (t=9.709, P＜0.001) than those without radial artery calcification. In MHD group, patients with abdominal aortic calcification had older age (t=2.033, P=0.048), and higher levels of phosphorus (t=2.360, P=0.023), alkaline phosphatase (t=2.122, P=0.040), immunoreactive parathyroid hormone (t=2.130, P=0.039) and serum sclerostin (t=2.671, P=0.011) than those without abdominal aortic calcification. ROC curve analysis showed that the area under the curve of serum sclerostin for prediction of VC in AVF group was 0.895 (95% CI 0.815~0.976, P＜0.001); at the optimal cut-off value of serum sclerostin 5.55ng/ml, the sensitivity of for the diagnosis of VC was 82.4%, the specificity was 86.4%. The area under the curve of serum sclerostin for prediction of abdominal aortic calcification in MHD group was 0.746 (95% CI 0.593~0.898, P=0.007); at the optimal cut-off value of 6.8555ng/ml, the sensitivity for the diagnosis of abdominal aortic calcification was 71.4% and the specificity was 81.2%. Conclusion VC was positively correlated with age, serum phosphorus, immunoreactive parathyroid hormone and serum sclerostin. Metrics

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Effect of online hemodiafiltration on quality of life of maintenance hemodialysis patients: a systematic review 2020, 19 (05):  294-297.  doi: 10.3969/j.issn.1671-4091.2020.05.002 Abstract ( 319 )   PDF (378KB) ( 784 )   【Abstract】Objective To systematically evaluate the effect of online hemodiafiltration (OL-HDF) on quality of life of maintenance hemodialysis (MHD) patients. Methods We used computer to search for the random and control studies about the effect of OL-HDF on quality of life of MHD patients during the period from the establishment of the databases to Aug. 30, 2019 in PubMed, Web of Science, Cochrane library, CNKI, VIP and Wan fang databases. Literature screening, data extraction, and the bias assessment of all eligible studies were independently conducted. RevMan 5.3 software was used for meta analyses. Results A total of 12 random and controlled trials involving 17,728 patients were included.The results showed thatOL-HDFcould improve the negative emotions (SMD=1.112, 95%CI 0.081~2.142, P=0.040) and social activity (SMD=0.467, 95% CI 0.032~0.886, P=0.042) in MHD patients. OL-HDF showed no significant differences in physiologyrelated quality of life (SMD=- 0.051, 95% CI - 0.155~0.053, P=0.332), psychology- related quality of life (SMD=-0.041, 95% CI -0.141~0.076, P=0.483) and fatigue (SMD=0.352, 95% CI -0.469~1.163, P=0.403), as compared those in patients with conventional hemodialysis. Conclusions OL-HDF has better effects on improving negative emotion and social activities in MHD patients. However, there are no significant differences in physiology and psychology-related quality of life and fatigue between patients with OL-HDF and conventional hemodialysis. Metrics

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Multivariate analysis of risk factors affecting left ventricular diastolic dysfunction in patients with maintenance hemodialysis 2020, 19 (05):  298-300.  doi: 10.3969/j.issn.1671-4091.2020.05.003 Abstract ( 248 )   PDF (356KB) ( 736 )   【Abstract】Objective To investigate the risk factors for left ventricular diastolic dysfunction (LVDD) in maintenance hemodialysis (MHD) patients. Method According to the diastolic function index, the 92 MHD patients were divided into two groups: LVDD group and normal left ventricular diastolic function group. Demographic characteristics, laboratory and body composition indexes were compared between the two groups. Logistic regression was used to analyze the risk factors for LVDD in MHD patients. Result In this cohort, 23(25.00%) patients had LVVD. Logistic analysis showed that overhydration (OR=1.824, 95% CI:1.124～2.960，P=0.015) was the independent risk factor for LVDD. Conclusion Patients with higher level of overhydration were independently associated with an increased risk of LVDD. Metrics

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Study on the improvement of malnutrition and mineral bone metabolism in dialysis patients by electronic intelligent assistant tools  2020, 19 (05):  301-304.  doi: 10.3969/j.issn.1671-4091.2020.05.004 Abstract ( 240 )   PDF (512KB) ( 716 )   【Abstract】Objective To explore the effects of electronic intelligent assistant tools on improving malnutrition and mineral bone metabolism in dialysis patients. Methods A total of 136 patients with mineral bone abnormalities and treated with dialysis in our hospital from Oct. 2018 to Oct. 2019 were divided into a control group (traditional management group) and a research group (intervention by electronic intelligent assistant tools) by using the single and double number random method. Electronic intelligent assistant tools were integrated into the nutrition management of dialysis patients. In control group, conventional dialysis treatment, standard medication and auxiliary education and guidance are given; in research group, electronic intelligent assistant tools were integrated into nutrition guidance in addition to the conventional dialysis treatment and nursing. After 12 months, hemoglobin, albumin, malnutrition inflammation score (MIS), blood calcium, phosphorus and iPTH levels and their compliance rates were determined. Results After the enrollment for 12 months, albumin (t=- 3.113, P=0.003) and hemoglobin (t=- 3.176, P=0.002) were significantly higher in research group than in control group; the MIS score was significantly lower in research group than in control group (t=2.486, P=0.024). The compound dialysis modalities (χ2=0.762, P=0.437), and use of non- calciumphosphate-containing binders (χ2=0.697, P=0.680), active vitamin D (χ2=0.029, P=0.500) and erythropoietin (χ2=0.299, P=0.136) had no significant differences between the two groups. The compliance rate of serum calcium was 57.4% in research group, significantly higher than that (30.9%) in control group (χ2=10.206, P=0.002). Serum phosphorus was significantly lower in research group than in control group (t=2.170, P=0.043), and the compliance rate of serum phosphorus was significantly higher in research group than in control group (χ2=7.909, P=0.007). The average level of iPTH was lower in research group than in control group (t=2.865, P=0.005). The average level of calcium-phosphorus product was (3.47±0.73) in research group, lower than that (4.89 ± 0.88) in control group (t=2.610, P=0.016). Conclusion Use of electronic intelligent assistant tools for the management of diet can improve calcium and phosphorus metabolism disorders and malnutrition in dialysis patients. Metrics

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Effect of the transtheoretical model and stages of change on improving the clinical symptoms and quality of life in patients with peritoneal dialysis  2020, 19 (05):  305-309.  doi: 10.3969/j.issn.1671-4091.2020.05.005 Abstract ( 253 )   PDF (474KB) ( 696 )   【Abstract】Objective To investigate the effect of the transtheoretical model and stages of change (TTM) on improving the symptoms and quality of life in patients with peritoneal dialysis (PD). Methods A total of 284 PD patients treated in our hospital were recruited and randomly divided into study group or control group. Both groups received the standard protocol of treatment plan, dietary and general activity guidance; the study group used TTM intervention in addition to the standard protocol. Interventions were carried out through five steps: unintended phase, intent phase, preparation phase, action phase and maintenance phase. Behavior change, incidence and degree of clinical symptoms, and quality of life score were compared between the two groups after the intervention for 12 months. Results There were no significant differences in the incidence and degree of clinical symptoms between the two groups before the intervention (P>0.05). After the intervention for 12 months, exercise increased (t=-3.011, P＜0.001), and the rates of smoking (χ2=34.841, P<0.001) and drinking (χ2=11.17, P=0.001) decreased in study group compared to those in control group; the incidence and severity of dry skin (χ2=0.271, P=0.697; t=1.325, P=0.166), insomnia (χ2=0.147, P=0.797; t=0.484,P=0.881), fatigue (χ2=0.147, P=0.798; t=0.345, P=0.667), skin itch (χ2=0.138, P=0.804; t=0.251, P=0.487), lower extremity edema (χ2=0.059, P=0.903; t=0.244, P=0.491), dry mouth (χ2=0.014, P=0.905; t=1.137, P=0.202), joint pain (χ2=0.057, P=0.905; t=0.631, P=0.587), cough (χ2=0.057, P=0.905; t=0.635, P=0.399), breath shortness (χ2=0.018, P=0.895; t=1.229, P=0.111) and dizziness (χ2=0.059, P=0.903; t=1.363, P=0.269) were significantly lower in study group than in control group. At the time of enrollment, scores of the 8 dimensions in the quality of life SF- 36 scale were lower in both groups. After the enrollment for 6 months, the scores of PF (t= 2.542, P=0.016), RP (t=3.778, P＜0.001) and REP (t=2.741, P=0.003) were significantly higher in study group than in control group. After the enrollment for 12 months, the scores of PF (t=4.207, P＜0.001), RP (t=1.921, P＜0.001), BP (t= 2.532, P=0.017), GHP (t=2.921, P=0.027), VT (t=2.214, P=0.027)and REP (t=2.031, P=0.019) were significantly higher in study group than in control group. Conclusion TTM can change the abnormal behavior and lifestyle, reduce the incidence of symptom groups, and improve quality of life in PD patients. Metrics

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Clinical application of overhydration regression formula to predict volume load for the individualized titration of dry weight in hemodialysis patients 2020, 19 (05):  310-313.  doi: 10.3969/j.issn.1671-4091.2020.05.006 Abstract ( 220 )   PDF (409KB) ( 665 )   【Abstract】Objective We first established a formula for calculating overhydration (OH) in healthy population in the local region, and then used this formula to titrate the target dry body weight and to observe the 24-hour ambulatory blood pressure monitoring (ABPM) changes and the incidence of adverse events in maintenance hemodialysis (MHD) patients. Methods The first stage of the study was an observational study, which enrolled 314 healthy people after physical examinations at Baotou Central Hospital. Body composition monitor (BCM) was used to measure their volume load status and body composition. The OH-related multiple regression formula was obtained by multivariate linear regression analysis. The second stage was an intervention study, which enrolled MHD patients with OH and mean 24-hour ABPM ≥130/80 mmHg. The OH-related regression formula was applied to titrate the target dry weight. Results The multivariate linear regression formula for OH in healthy people is OH=6.203-0.019× Y-0.083×G-0.006×F+0.098×L-1.437×P (F=189.896, R2=0.755, P＜0.001; Y: age; G: sex; F: lipid ass; L: lean tissue mass; P: phase angle). Eight MHD patients were enrolled in the study. After adjustment, 75% of the patients had a dry weight compliant with the target value. The 24-hour ABPM showed that the proportion of systolic blood pressure≥180mmHg decreased from 30.188 ± 15.957% to 4.088 ± 2.719% (t=4.831, P=0.002), and the proportion of systolic blood pressure ≤ 159mmHg increased from 28.713±24.672% to 71.688±16.545% (t=-6.207, P= 0.001). Conclusion The OHrelated calculation formula obtained from healthy population can be used for dry body weight management individually in MHD patients. Metrics

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Treatment of anti- MDA5 positive dermatomyositis complicated with rapidly progressive interstitial lung disease by hemoperfusion and drugs: a retrospective analysis of 12 cases  2020, 19 (05):  314-316.  doi: 10.3969/j.issn.1671-4091.2020.05.007 Abstract ( 352 )   PDF (407KB) ( 669 )   【Abstract】Objective To investigate the efficacy and safety of hemoperfusion combined with drugs for the treatment of anti-MDA5 positive dermatomyositis complicated with rapidly progressive interstitial lung disease (RP- ILD). Methods We retrospectively studied 12 anti-MDA5 positive dermatomyositis patients complicated with RP-ILD hospitalized in the period from March 2016 to November 2018. They were treated with HA-280 resin hemoperfusion apparatus for hemoperfusion and the drugs of methylprednisolone, tacrolimus and/or cyclophosphamide. Their peripheral blood lymphocyte count, serum IL-6, IL-10, CRP, Krebs Von den Lungen-6 (KL-6) and ferritin, arterial partial pressure of O2 and CO2, and lung high resolution computed tomography (HRCT) score were recruited before and after the treatment. ANOVA was used to analyze the data before the treatment and after the treatment for 2 and 4 weeks. LSD-t test was used for the comparison of two groups of data. Results After the treatment for 4 weeks, serum IL-6、IL-10 、KL-6 、ferritin and CRP decreased significantly (F=6.593, 9.029, 7.872, 8.760, 20.490；P=0.005, 0.001, 0.002, 0.001, ＜0.001). Arterial O2 partial pressure、arterial CO2 partial pressure、peripheral blood lymphocyte count improved significantly (F=3.580, 3.467, 16.810；P=0.042,0.046,＜0.001), as compared to those before the treatment. HRCT score (F=2.073, P=0.145) also improved but without statistical significance. Conclusion Hemoperfusion combined with methylprednisolone, tacrolimus and/or cyclophosphamide were effective and safe for the treatment of anti-MDA5 positive dermatomyositis complicated with RP-ILD. Metrics

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Selection and status of vascular access in elderly dialysis patients 2020, 19 (05):  320-322.  doi: 10.3969/j.issn.1671-4091.2020.05.009 Abstract ( 231 )   PDF (249KB) ( 883 )   Metrics

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Research progress in the risk factors and intervention measures for sarcopenia in hemodialysis patients 2020, 19 (05):  323-326.  doi: 10.3969/j.issn.1671-4091.2020.05.010 Abstract ( 277 )   PDF (358KB) ( 715 )   【Abstract】This paper reviews the risk factors and intervention measures for sarcopenia in hemodialysis patients, in order to raise the alertness in medical staff on sarcopenia in hemodialysis patients, and to provide references for clinicians to carry out intervention measures for the sarcopenia. Metrics

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Research progress in the role and mechanism of asymmetric dimethylarginine in chronic kidney disease 2020, 19 (05):  327-329.  doi: 10.3969/j.issn.1671-4091.2020.05.011 Abstract ( 267 )   PDF (395KB) ( 795 )   【Abstract】Asymmetric dimethylarginine (ADMA) is a potent endogenous nitric oxide synthase (NOS) inhibitor, which competitively inhibits NOS activity, reduces the production of nitric oxide (NO), and participates in the pathological process of renal fibrosis. The role of ADMA in chronic kidney disease (CKD) is unclear, and the traditional view is that the increase of ADMA plasma level is closely related to the poor prognosis of CKD and is an independent predictor of CKD events. The most recent point of view is that the reduction of local ADMA metabolism in the kidney prevents the deterioration of renal function and renal fibrosis. This paper introduces ADMA in its production, regulation and control mechanism, assay method, and the drugs targeting ADMA in chronic kidney disease, and focuses on the two points of view mentioned above relating to its basis and clinical research progress. Metrics

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tudy on the maturation and hemodynamics of newly built autologous arteriovenous fistulas in diabetic nephropathy patients 2020, 19 (05):  330-333.  doi: 10.3969/j.issn.1671-4091.2020.05.012 Abstract ( 212 )   PDF (408KB) ( 804 )   【Abstract】Objective To study the difference of the maturation of autologous arteriovenous fistula (AVF) between the patients with type 2 diabetic nephropathy and those with non-diabetic nephropathy, and to provide suggestions for dialysis treatment and nursing in these patients. Methods Sixty patients with diabetic nephropathy and treated in the period from January 2017 to July 2019 were recruited as the observation group, and 60 patients with non-diabetic nephropathy in the same period were randomly selected as the control group. Maturation of AVF and hemodynamic parameters of the patients in the two groups were examined by physical examination and color Doppler ultrasound and then analyzed retrospectively. Results ①In observation group, the average maturation period of AVFs was 88.25±7.30 days, the average internal diameter of cephalic vein was 4.85±1.31 mm, and the average blood flow was 586.49±78.33 ml/min, significantly different from those in control group (t=-20.591, P<0.001 for maturation period; t=3.385, P=0.001 for cephalic vein diameter; t=4.667, P<0.001 for blood flow). ②in observation group, the diameter of radial artery was smaller than that in control group before the surgery (t=2.224, P= 0.029), and remained smaller after maturation (t=-3.134, P=0.002). The periods of internal diameter of cephalic vein and blood flow rate to the maturation values were 2 and 4 weeks in control group and observation group respectively. Conclusion The maturation and hemodynamics of AVF after the surgery are different between patients with diabetic nephropathy and those with non-diabetic nephropathy. These differences are of great significance in accurate determination of the AVF maturity, the time suitable for blood access, and successful performance of hemodialysis. Metrics

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The effects of thrombolysis using urokinase combined with percutaneous transluminal angioplasty in the treatment of acute thrombosis in arteriovenous graft 2020, 19 (05):  334-337.  doi: 10.3969/j.issn.1671-4091.2020.05.013 Abstract ( 218 )   PDF (491KB) ( 830 )   【Abstract】Objective To assess the safety and effectiveness of thrombolysis using urokinase combined with percutaneous transluminal angioplasty in the treatment of acute thrombosis in arteriovenous graft (AVG). Methods The clinical data of 20 patients with acute thrombosis in AVG and treated during the period from January 2017 to December 2018 were retrospectively analyzed. The diagnosis of acute thrombosis in AVG was confirmed by vascular ultrasound examination in all patients. After thrombolysis using urokinase, a syringe was used to repeatedly aspirate the thrombosis via the vascular sheath until no further thrombi could be aspirated, and angioplasty was then performed at the stenosis site as required. Technical success rate, complications and patency rate were analyzed. Results Technical success was achieved in all 20 cases (100 %). One case had hematoma at the puncture site, and the other cases had no complications. Primary patency rates were 100%, 87.5% and 75.0% after 3, 6, and 12 months, respectively. The secondary patency rates were 100%, 100% and 95%, respectively. Conclusions Thrombolysis using urokinase combined with percutaneous transluminal angioplasty in the treatment of acute thrombosis in AVG is safe and effective. Metrics

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Quality improvement of standardized hemodialysis installation and pre- flush: a multicenter study 2020, 19 (05):  338-341.  doi: 10.3969/j.issn.1671-4091.2020.05.014 Abstract ( 343 )   PDF (391KB) ( 879 )   【Abstract】Objective To improve the quality of care in installation and pre-flush for hemodialysis therapy by applying a quality control checklist. Methods A quality control checklist to standardize the installation and pre-flush was designed and used as an evaluation tool to investigate 11 hemodialysis institutions/centers during the priming process. The medical workers in the 11 dialysis centers were then trained according to content in the checklist. The processes of installation and pre-flush of each dialysis unit were evaluated and the efficacy of the training was obtained and discussed after training. Results There was no significant difference in the priming time before and after the quality improvement (27.05 ± 4.59 vs. 27.50 ± 4.03 min; t= -0.296, P=0.774). All of the compliance rates were improved after quality improvement, and the overall score was higher after the training compared to that before the training (t=-3.993, P=0.003). All of the 11 dialysis centers considered that the checklist was quite simple and practical. Conclusion The priming quality control checklist is convenient and practical for training and evaluation. This checklist can be used by the clinical quality managers as a regular evaluation method for the quality control of installation and pre-flush for hemodialysis therapy. Metrics

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Nursing care of the patients with urgent- start peritoneal dialysis using automated peritoneal dialysis 2020, 19 (05):  342-345.  doi: 10.3969/j.issn.1671-4091.2020.05.015 Abstract ( 182 )   PDF (531KB) ( 680 )   【Abstract】Objective To observe the therapeutic effect, clinical parameters and complications of automated peritoneal dialysis (APD) for patients with urgent-start dialysis, and to summarize the suitable and scientific nursing methods for APD. Methods Thirty patients treated with APD in the Department of Nephrology, Beijing Chaoyang Hospital Affiliated to Capital Medical University were enrolled as the APD group, and 30 patients treated with continuous ambulatory peritoneal dialysis (CAPD) were randomly selected as the CAPD group. Clinical parameters, catheter- related complications and ultrafiltration volume in the processes of urgent-start peritoneal dialysis were observed in the two groups. Results In the first week, the average ultrafiltration volume was higher in APD group than in CAPD group (721.133 ± 392.830 ml vs. 354.833 ±157.011 ml; t=1.743，P＜0.001); serum creatinine was similar between APD group and CAPD group (655.295±161.847 μmol/L vs. 763.629±301.200 μmol/L; F= 3.011, P=0.088); urea nitrogen was lower in APD group than in CAPD group (18.803 ± 6.122 mmol/L vs. 25.542 ± 7.364 mmol/L; F=14.855, P<0.001). In the second week, serum creatinine was lower in APD group than in CAPD group (568.706 ± 133.833 μmol/L vs.716.389±267.045 μmol/L; F=7.333, P=0.009); urea nitrogen was lower in APD group than in CAPD group (17.269±5.499 mmol/L vs. 21.637±6.383 mmol/L; F=8.061, P=0.006). In the fourth week, serum creatinine was lower in APD group than in CAPD group (520.512 ± 111.881 μmol/L vs. 657.069 ± 281.012 μmol/L;F=6.115, P=0.016); urea nitrogen was lower in APD group than in CAPD group (14.376±4.502 mmol/L vs. 18.197±4.583mmol/L; F=10.614,P=0.002). Complications occurred in the two groups: peritonitis within the first month, 0 case in APD group and one case in CAPD group (χ2=1.017, P=0.313); leakage, 0 case in APD group and one case in CAPD group (χ2=1.017, P=0.313); exit or tunnel infection, one case in each group (χ2=0.000, P=1.000); intraperitoneal hemorrhage, one case in APD group and 2cases in CAPD group (χ2=0.351, P=0.554); abdominal pain, 2 cases in each group (χ2=0.000, P=1.000); tube displacement, 0 case in APD group and 2 cases in CAPD group (χ2=2.069, P=0.150); inadequate drainage, 4 cases in each group(χ2=0.000, P=1.000). Conclusion Automated peritoneal dialysis is a new method of urgent-start dialysis and is clinically useful. This method causes less disturbance to patients’rest and dialysis training as well as less workload to nurses. Metrics

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A survey of diabetic foot care behavior in peritoneal dialysis patients and the risk factors of composite end points 2020, 19 (05):  346-349.  doi: 10.3969/j.issn.1671-4091.2020.05.016 Abstract ( 203 )   PDF (392KB) ( 618 )   【Abstract】Objective To understand the nursing behavior of diabetic foot in peritoneal dialysis (PD) patients, to follow up the incidence of new foot ulcer and other composite end points, and to explore the influencing factors. Methods A single center cohort design was conducted to enroll the clinical stable diabetic PD patients who received regular follow- up in our peritoneal dialysis center from January to June 2014. Their baseline data, foot care behavior and frequency were recorded. All patients were followed up to December 31, 2018. Composite end points included new foot ulcers, amputations due to foot ulcers or gangrene, and revascularization of lower extremity vessels. Results A total of 108 patients were included. The average follow-up time was 26.0 (15.0, 45.0) months. Seventeen patients (15.7%) had a composite end point, with an incidence rate of 71.9/ 1,000 patients. The highest incidence of high-risk behavior in diabetic foot care was wearing sandals or slippers (67.6%). After adjustment of age, gender, diabetes years and other factors, walking barefoot HR:7.533,95% CI 2.073～27.370,P=0.002 and wearing sandals or slippers HR:3.198,95% CI 1.212～8.436, P=0.019 were the independent risk factors. Conclusion Seventeen patients (15.7%) in this group had foot ulcer. Walking barefoot and wearing sandals or slippers were the independent risk factors for predicting new foot ulcer, suggesting that diabetic foot education should be strengthened in PD patients to avoid the high-risk behaviors. Metrics

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Study on the correlation between resilience, perceived social support and quality of life in young and middle-aged maintenance hemodialysis patients 2020, 19 (05):  350-352.  doi: 10.3969/j.issn.1671-4091.2020.05.017 Abstract ( 287 )   PDF (351KB) ( 911 )   【Abstract】Objective To explore the psychological elasticity of young and middle-aged maintenance hemodialysis (MHD) patients and to understand the relationship between social support and quality of life, so as to provide theoretical basis for improving the quality of life of young and middle- aged MHD patients. Methods Connor- Davidson Resilience Scale, Perceived Social Support Scale (PSSS) and Kidney Disease Quality of Life Scale (KDQOL-36TM) were used to investigate 110 young and middle-aged MHD patients in a hemodialysis center of the university hospital in Chengdu city. Descriptive statistics, Pearson correlation analysis and intermediary effect test were used to analyze the correlation. Result The total CD-RISC score in the middle-aged and young MHD patients was 64.75 ±18.57, among which the score of resilience was the lowest; the total score of perceived social support was 62.23±12.83, and the score of friend support was the lowest; the average score of quality of life was 58.37±15.46, among which the score of kidney burden was the lowest. Social support and quality of life (r=0.238, P= 0.017), psychological resilience and quality of life(r=0.413,P=0.001), and perceived social support and psychological resilience (r = 0.421, P = 0.001) were positively correlated in young and middle-aged MHD patients. Psychological elasticity played an intermediary role in social support and quality of life, and the intermediary effect accounted for 89.4% of the main effect. Conclusion The quality of life in young and middle-aged MHD patients can be improved by promoting their psychological elasticity and social support. Metrics

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Clinical observation on the reaction of polysulfone membrane dialyzer in single center hemodialysis patients 2020, 19 (05):  357-358.  doi: 10.3969/j.issn.1671-4091.2020.05.019 Abstract ( 239 )   PDF (227KB) ( 794 )   Metrics

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A case of Soft tissue calcification recurrence and infection in maintenance hemodialysis patients after parathyroidectomy 2020, 19 (05):  359-360.  doi: 10.3969/j.issn.1671-4091.2020.05.020 Abstract ( 308 )   PDF (648KB) ( 757 )   Metrics