Abstract: 【Abstract】Objective To explore the preventive effect of hydrocolloid dressing and 3M dressing on tunnel orifice infection in peritoneal dialysis (PD) patients, and to analyze the risk factors for the catheter orifice infection. Methods A total of 154 PD patients admitted to the Department of Nephrology of Chengde Central Hospital from June 2018 to December 2020 were recruited and divided into hydrocolloid dressing group (n=86) and 3M dressing group (n=68) according to the type of tunnel orifice dressing at the time the dialysis started. The infection control rate and cure rate before discharge from the hospital were compared between the two groups. The cure time, the number of dressing changes and adverse reactions were analyzed. Patients were also divided into infection group and non-infection group according to the situation of tunnel orifice infection. Logistic regression was used to analyze the risk factors for tunnel orifice infection. Results The infection rate was statistically lower in the hydrocolloid dressing group than in the 3M dressing group (4.65% vs. 14.71%; U=2.005, P=0.045). The proportions of poor tube fixation, incompliance with orifice care procedures and orifice mechanical compression were significantly lower in the non-infection group than in the infection group (χ2=6.755, 4.200 and 5.468 respectively; P=0.009, 0.040 and 0.019 respectively). Logistic regression
showed that poor fixation of the tube (OR=1.793, 95% CI:1.060~3.032, P=0.029) and dressing type (OR=1.592, 95% CI: 1.065~ 2.379, P=0.023) were the risk factors for tunnel orifice infection. Conclusion The hydrocolloid dressing reduced the incidence of tunnel orifice infection in PD patients and facilitated healing of the infection with safety. Careful should be paid to fix the PD tube, to guide the patients following the orifice nursing processes, and to avoid mechanical pressure on the orifice during nursing PD patients.

Key words: Hydrocolloid dressing, 3M dressing, Peritoneal dialysis, Tunnel orifice infection, Nephropathy