Abstract: Non-bioartificial liver has been used clinically as a main therapy of extracorporeal artificial liver support system for severe liver diseases. However, little was known about the influences of this system on organs other than liver. The information about these influences is important for the further improvement of artificial liver. In this paper, we review the effects of non-bioartificial liver on renal function, blood cells, blood coagulation system, cytokines and survival, as well as its adverse effects.

Key words: Non-bioartificial liver