Abstract: 【Abstract】Objective To investigate and analyze the biochemical variables under the influence of different levels of serum intact parathyroid hormone and other associated factors of patients undergoing maintenance hemodialysis. Methods 93 CKD patients undergoing maintenance HD were divided into 3 groups according to their serum iPTH level (group A 300 ng/L) Compare the age, prevalence of diabetes, duration on dialysis, body weight, BMI and other serum biochemical variables of patients in 3 groups. The relation between age, gender, diabetes mellitus, duration on dialysis, serum calcium (Ca), phosphorus (P), alkaline phosphates (ALP) were examined by multiple linear regression analysis. Results The serum creatinine and P were significantly higher in group B and C than those in group A (P<0.05). In group C, duration on dialysis, serum Ca and ALP were remarkably higher than those in group A and B (P <0.05). The duration on dialysis and serum albumin(ALB) in group B were obviously elevated as compared with those in group C(P <0.05). From group A to C, There was a decline of diabetes morbidity (P =0.003). There was a positive correlation between duration on dialysis, serum P and iPTH (b=0.102, b=3.077) while a negative correlation between diabetes mellitus and iPTH(b =-1.294).Conclusions the prognoses of patients on maintenance hemodialysis were under the influence of iPTH level. iPTH level was positively related with duration on dialysis and serum P, while it was negatively related with diabetes. [Key words] Chronic kidney disease; Hemodialysis; Intact parathyroid hormone

Key words: [Key words] Chronic kidney disease, Hemodialysis, Intact parathyroid hormone