Abstract: Abstrac Objective To explore the impact of  dyslipidemia on ultrafiltration failure(UFF)  in peritoneal dialysis patients. Method Choosed 124 patients who accepted  peritoneal dialysis regularly  for more than 12 months. Measured  ALB,Hb,T-Ch,TG,LDL-C,HDL-C,BUN,Cr,Glu of the patients. Recorded  the age of the patients. Patients were divided into dyslipidemia group and  normal lipid group according to the results of the blood lipid. The incidence of UFF in two groups was compared.Divided into the groups according to UFF or not. The differences of the level of  lipid 、renal function、Glu、ALB、Hb in two groups were compared. Results he incidence rate of UFF through the peritoneal dialysis in dyslipidemia group was obviously higher than in the normal blood lipids group（P=0.008）.The duration of dialysis in UFF group was longer than in the ultrafiltration normal group（T=7.93,P=0.000）.The systolic blood pressure and diastolic blood pressure in UFF group was obviously higher than in the ultrafiltration normal group（T_SBP=7.36, P_SBP=0.000,T_DBP=4.51,P_DBP=0.000）.The level of TG and T-Ch in UFF group was apparently higher than in the normal group（T_T-Ch=3.45,P_T-Ch=0.001；T_TG=6.76,P_TG=0.000）,while the level of HDL-C was obviously lower（T=－7.53,P=0.000）,The incidence rate of low peritoneal transport in dyslipidemia group was obviously higher than in the normal blood lipids group（P=0.021）.Multivariate analysis showed that long duration of dialysis and the low level of HDL were independent risk factors for ultrafiltration failure through the peritoneal dialysis.(p=0.034、0.048). Conclusion 1 Dyslipidemia in peritoneal dialysis patients is one of the causes of UFF.UFF in dyslipidemia patients is related to high TG、T-Ch level and low HDL-C level. 2. UFF in dyslipidemia patients maybe caused by deducing the turn-over capacity of the peritoneum. 3.Long term of dialysis and low HDL level are independently dangerous risks for peritoneal dialysis.

Key words: Peritoneal dialysis, Dyslipidemia, dislipidemi, ultrafiltration failure