Abstract: 【Abstract】Objective To establish system of regular water of hemodialysis and detecting toxin in dialysate,and to probe into the reasonable limiting range of water of hemodialysis and detecting toxin in dialysate, in purpose of decreasing the risk of hemodialysis treating. Methods According to Bacterial endotoxin photometricdetection method which is included in Chinese Pharmacopoeia(Ch.p) 2010 second edition, experimenting by adopting ATI dynamic test tube apparatus to quantitive determinate reverse osmosis(RO) and volumeof toxin in dialysate(reference to ISOStandard). Results after scrutiny for fifteen hospital in total, it is found that toxin in dialysate of above including fourteen hospital is Below 0.25EU/ml, qualified rate reach93.3 percent, and eight hospital is below 0.50 EU/ml, qualified rate reach53.3 percent. after rectification，rate of RO and dialysate reach 100 percent. Conclusions As a result of strengthening persistent quality control in each progress for hemodialysis, taking intervention timely,and improving quality of hemodialysis, to decrease
treating risk of hemodialysis is wholly possible and feasible.

Key words: Hemodialysis, Dialysate, Reverse Osmosis(RO), Endotoxin, Treatment Risk