Abstract: Diabetes mellitus (DM) is the leading cause of end-stage renal disease (ESRD) in many countries. Most diabetic patients with ESRD are maintained on renal replacement therapy. Compared with patients without diabetes, patients with diabetes on dialysis generally have poorer survival rates because of a higher incidence of complications and comorbidities.The question on timing of start of dialysis and optimal first choice of dialysis modality in diabetes mellitus patients remains a matter of debate. Peritoneal dialysis (PD) offers multiple benefits for the treatment of ESRD patients with diabetes, however PD is also associated
with certain negative factors inherent to the use of this modality. The present review addresses the strategies for the care of diabetic PD patients.With improved fluid balance, better glycemic control, optimal preservation of residual renal function and peritoneal function as well as the reducing risk factors of cardiovascular disease, there is hope for improving the long-term outcomes of diabetic PD patients.

Key words: Diabetes mellitus, End-stage renal disease, Peritoneal dialysis, Clinical outcomes