Abstract: Objective To investigate the family caring support,the environment and sanity,the life quality and family economic burden to afford the medical expenses of peritoneal dialysis patients,we discussed about the risk factors for peritonitis taking place in patients accepting peritoneal dialysis. Method Questionnaire
on peritoneal patients who ungerwent the peritoneal dialysis in our center for at least 3 months and followed up steadily with regularly evaluating results for their dialysis effects.Combined with the patients' personal clinical information,including the results of experimental tests,the follow-up evaluation on dialysis,and the total occurence of peritonitis,related statistics were analyzed to find out risk factors for peritonitis.Results Among the 166 PD patients,103 cases were males(62.4%),the average age at the beginning of PD was 57.88±17.31 years.Up to December 2015, totally 55 cases(33.13%) went on peritonitis in the observing period.LOGISTIC proportional hazards model analysis indicated that the risk factors for peritonitis were ：age at the beginning of PD (OR=1.054，95% CI 1.007～1.104，P=0.025),high blood level of 1,25-OH-D3(P=0.033, 95%CI: 1.003～1.090，OR=1.045),and the influence of PD expenditure on family economics (OR=0.371，95% CI 0.149～0.923，P=0.037). Compared with the non-peritonitis,the peritonitis group had longer duration of peritoneal dialysis (Z=-6.796，P＜0.001),higer value of kt/v and CCR (Z=-2.174，P=0.030),and higher rate of involvement in social work and study (Z=-2.286，P=0.022). Conclusion In the PD patients treated in our center, family caring support, environment and sanity, and quality of life were basically in good conditions, and medical expenses
were acceptable to most PD families. Older age at the beginning of PD, higher plasma 1,25-OH-D3 before PD were the risk factors for PD-related peritonitis. The peritonitis rate was relatively lower in the families considering PD as a big financial burden. More involvement in social work or study, longer PD duration, and insufficient clearance of toxic solutes also contributed to the presence of peritonitis.

Key words: petironeal dialysis, peritonitis, Investigation