Abstract: 【Abstract】Object To study the significance of body composition monitor (BCM) for the assessment of blood pressure changes in maintenance hemodialysis (MHD) patients. Methods A total of 126 MHD patients and treated in Renji Hospital Shanghai Jiaotong University School of Medicine and analyzed by BCM were recruited. The values of pre- dialytic overhydration (OH), expected ultrafiltration volume, actual ultrafiltration volume, intradialytic blood pressure change, and interdialytic blood pressure were recorded. Results ①The pre-dialytic OH value was lower in hypotension group than in non-hypotension group (1.48±1.26 vs. 2.13±1.22, P=0.017). The difference between pre-dialytic OH and expected ultrafiltration volume was lower in hypotension
group than in non- hypotension group (-2.10±1.23 vs. -1.18±1.19, P=0.001). ②The interdialytic mean artery pressure (MAP) was positively correlated with the pre-dialytic OH value (r=0.301, P=0.003), and was also positively correlated with the difference between pre-dialytic OH value and actual ultrafiltration volume
(r=0.227, P=0.028). ③When the difference between pre-dialytic OH value and actual ultrafiltration volume was used to predict the interdialysis hypertension in MHD patients, the area under the ROC curve was 0.681 (0.586～0.776, P=0.001). ④ When the difference between pre-dialytic OH value and expected ultrafiltration volume was used to predict the intradialytic hypotension in MHD patients, the area under the ROC curve was 0.721 (0.607～0.835, P=0.001). Conclusion The difference between pre-dialytic OH value from BCM and the actual ultrafiltration volume can be used to predict the risk of interdialysis hypertension; the difference between pre-dialytic OH value from BCM and the expected ultrafiltration volume can be used to predict the risk of intradialysis hypotension in MHD patients.

Key words: Body composition monitor, Blood pressure, Ultrafiltration volume