Abstract: 【Abstract】Objective To compare the quality of dialysis water and dialysate among different hemodialysis(HD) centers from different areas. Methods The records regarding to quality control of dialysis water and dialysate in 2017 were collected from 43 HD centers located in the 3 areas (ZK, SQ, and CP). A questionnaire survey was conducted in order to analyze the factors for failure to pass quality examinations. Results Three centers from SQ area failed to pass quality examinations in 2017 because of management problems. Eight of the other 40 centers failed to pass the examinations; the dialysate from these centers had bacterial culture (77.50±44.57 CFU/ml vs. 17.52±20.00 CFU/ml, t=5.663, P=0.000) and endotoxin levels (0.276±0.156 EU/ml vs. 0.094±0.063 EU/ml, t=4.893, P=0.000) higher than the standards, as compared with those of the 32 centers passed the quality examinations. There was significant difference in the endotoxin test method among the 3 cities. The ratio of samples examined in other places and those examined by themselves were 12/4 in ZK area, 2/11 in SQ area and 3/8 in CP area (χ2=10.933, P=0.004). All of the centers in ZK and SQ areas did not follow the new standards for quality control of dialysis water. Conclusion There were significant differences in quality control of dialysis water and dialysate among different HD centers. The use of new standards for water and dialysate qualify control should be emphasized.

Key words: Hemodialysis, Quality control, Dialysis water, Dialysate, Endotoxin