【Abstract】Aim To understand the changes of abdominal CT image and their influence factors in continuous ambulatory peritoneal dialysis (CAPD) patients with peritoneal injury. Methods A total of 173 CAPD patients regularly followed up in our center were subjected to abdominal CT scan. The relationship between the abnormal CT image indices and the clinical indices of age, dialysis age, primary disease, type of peritoneal transport, glucose exposure and number of peritonitis episodes were analyzed in 109 patients who met the criteria of peritoneal injury. Logistic regression was used to evaluate the influence factors for increased thickness of peritoneum and abnormal omental structure as well as the relationship between the number of peritonitis episodes and the increased thickness of peritoneum and abnormal omental structure. Results In the 109 patients

with peritoneal injury, 70 had increased thickness of parietal peritoneum (64.22%) and 63 showed abnormal omental structure (57.8%) on abdominal CT scan. Multivariate regression analyses revealed that the episode number and the cumulative score of peritonitis were the independent risk factors for increased thickness of peritoneum and abnormal omental structure. The risk prediction model suggested that the risks of peritoneal thickening and abnormal omental structure increased 4.364 (OR=4.364, 95% CI 1.886～10.098) and 5.393 (OR=5.393, 95% CI 2.204～13.197) times respectively after every episode of peritonitis. Conclusions The increased thickness of parietal peritoneum and abnormal omentum structure were the main imaging features in

CAPD patients with progressive peritoneal injury. The major risk factor for progressive peritoneal injury was peritonitis. Abdominal CT scan is useful to comprehensively investigate the characteristics and extent of peritoneal injury and to diagnose peritoneal injury earlier.