【Abstract】Objective To explore the risk factors for the re- hospitalization within six months due to chronic cardiac insufficiency in patients on continuous ambulatory peritoneal dialysis (CAPD). Methods We retrospectively analyzed 204 CAPD patients who were diagnosed chronic cardiac insufficiency from January 2017 to December 2018. Log-rank test for univariate analysis and Cox regression model for multivariate analysis were used to explore the cause of re-hospitalization due to chronic cardiac insufficiency in these CAPD patients. Results Re- hospitalization within six months happened in 59 cases with the recurrence rate of 28.92%. There are statistically differences in blood urea nitrogen (c2=3.765, P=0.017), serum pre- albumin (c2=6.021, P=0.001), systolic blood pressure (c2=4.652, P=0.015), diastolic blood pressure (c2=3.623, P=0.018), volume management (c2=6.211, P=0.001), edema degree (c2=6.041, P=0.001) between the two groups. Multivariate Cox regression analyses showed that volume management (95% CI 1.298～2.432, OR=2.003, P= 0.023), serum pre-albumin (95% CI 1.421～2.765, OR=2.112, P=0.001) and edema degree (95% CI1.021～2.002, OR=1.675, P=0.034) were the risk factors for re- admission within six months in CAPD patients. Conclusion Nurses working for CAPD patients should increase their abilities in volume management, improvement of nutritional status and edema classification to reduce the re-admission rate.