Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2020, Vol. 19 ›› Issue (01): 45-48.doi: 10.3969/j.issn.1671-4091.2020.01.012

Previous Articles     Next Articles

Hemoglobin concentration change and its related factors in maintenance hemodialysis patients with different method of vascular access#br#

  

  1. 1Department of Nephrology, Wuhan First Hospital, Wuhan 430022, China;  2Wuhan Blood Dialysis Quality Control Center, Wuhan 430022, China CHENG Li and MIN Yong-long contributed equally to this paper
  • Received:2019-03-29 Revised:2019-11-22 Online:2020-01-20 Published:2019-12-30

PDF

756

Abstract: 【Abstract】Objective To compare the difference of hemoglobin concentration (HB) and its related factors among maintenance hemodialysis (MHD) patients with two methods of vascular access (AVF and non-AVF) in Wuhan district. Methods The MHD patients from 40 dialysis units in Wuhan district were recruited as the research objects. Their general clinical information and biochemical indicators were collected. A total of 3,792 patients were enrolled in this study and divided into AVF group and non-AVF group. HB and other parameters were compared between the two groups. The effect of vascular access method on HB was then analyzed. Result ①The median value of spKt/V was significantly higher in AVF group than in non-AVF group (χ2=3.358, P=0.001). ②The average levels of HB, ALB, BUN and Ca were significantly higher in AVF group than in non- AVF group (t= 5.522, 13.297, 11.51 and 2.895 respectively; P＜0.001, ＜0.001, ＜0.001 and 0.004 respectively); while the average levels of Cr, P and logarithm value of PTH were significantly lower in AVF group than in non-AVF group (t=- 17.720, - 8.309 and - 3.773 respectively; P＜0.001, ＜0.001 and ＜0.001 respectively). ③ Pearson correlation analysis showed that HB was positively correlated with ALB (r=0.268, P＜0.001) and Ca (r=0.117, P＜0.001) and negatively correlated with P (r=-0.077, P=0.008) and logarithm value of PTH (r=-0.061, P=0.002) in AVF group; HB was negatively correlated with ALB (r=0.301, P＜0.001) and Cr (r=-0.131, P=0.006) in non-AVF group. ④The proportion of anemia (HB＜100g/L) was lower in AVF group than in non-AVF group (32.2% vs. 39.1%, χ2=16.043, P＜0.001). ⑤Logistic regression model after correcting various confounded factors showed that the risk of anemia in MHD patients with AVF was 19.5% lower than that in patients without AVF (OR=0.805, 95% CI 0.752～0.956, P=0.043). Conclusion HB level was higher and the risk of anemia was lower in MHD patients using AVF as blood access, as compared to those using the blood access routes other than AVF.

Key words: Maintenance dialysis, Vascular pathway, Anemia

CLC Number: