Abstract: 【Abstract】Objective To analyze the clinical characteristics of peritoneal dialysis (PD)-related peritonitis with different outcomes and to explore the risk factors for PD-related peritonitis. Methods We retrospectively analyzed the clinical data of PD patients with PD-related peritonitis hospitalized from Jan. 2004 to Dec. 2018 in The Second Affiliated Hospital of Harbin Medical University. They were divided into cure group and exit group (change to hemodialysis or death). Their clinical characteristics were compared between the two groups. Results A total of 180 PD patients with PD-related peritonitis were included in this study. There were no significant differences in age, gender, smoking history, complications and prevalence of hypokalemia
between the two groups. Compared to cure group, patients in exit group had lower plasma albumin (23.48±6.43 g/L vs. 26.84 ± 7.61 g/L, t=2.953, P=0.004) and hemoglobin (87.48 ± 19.34 g/L vs. 93.27 ± 17.50 g/L,t=2.028, P=0.044), higher fungal infection rate, higher referral rate (36.10% vs. 18.50%, χ²=6.747, P=0.009),and longer dialysis age [36.00 (12.66, 50.000) months vs. 24.00 (9.00, 42.00) months, Z=2.368, P=0.018). Multivariate logistic regression showed that longer dialysis age, referral to other department and relapse of peritonitis were the independent predictors for poor prognosis. Conclusion Nutritional status, anemia, referral to other department, relapse of peritonitis and dialysis age were associated with the prognosis in PD patients with peritonitis. Improvement of nutritional status, treatment of anemia will ameliorate the prognosis of PD patients with peritonitis.

Key words: Peritoneal dialysis-related peritonitis, Nutritional status, Risk factor, Referral