Abstract: 【Abstract】Objective To study the value of color Doppler ultrasound examination to find out complications in functional autogenous arteriovenous fistula (AVF) with target Kt/V value, to analyze the relationship between color Doppler ultrasound parameters and pump-controlled blood flow, and to evaluate the impact of color Doppler ultrasound findings on clinical practice. Methods A total of 68 maintenance hemodialysis (MHD) patients were enrolled in this study. Their clinical and biochemical data and color Doppler ultrasound examination results were collected. The patients were then divided into fistula stenosis group and non-fistula stenosis group. Results ①Color Doppler ultrasound examination found the many complications, including stenosis (23/68 cases, 33.8%), aneurysm (10/68 cases, 14.7%), thrombosis (11/68 case, 16.2%), calcification
(13/69 cases, 19.1%), vascular branches (23/68 cases, 33.8%), and distal radial artery reflux (17/59 cases, 28.8%). ② Compared with non-fistula stenosis group, fistula stenosis group had older age (t=2.559, P=0.013),more fistulas located at distal forearm (χ2=5.302,P=0.021), lower pump- controlled blood flow (t=- 2.710, P=0.009), smaller diameters of anastomosis orifice (t=-2.987, P=0.004) and brachial artery (t=-2.711, P=0.009), lower blood flow at the puncture site (t= -2.158, P= 0.035), and reduced blood flow in brachial artery (t=-2.657, P=0.010). Pearson correlation analysis showed that pump- controlled blood flow was positively correlated with the diameters of anastomosis orifice (r=0.452, P＜0.001), puncture site (r=0.441, P＜0.001), radial artery (r=0.469, P＜0.001) and brachial artery (r=0.445, P＜0.001), and blood flow volumes at the puncture site (r=0.369, P=0.002) and in brachial artery (r=0.384, P=0.001). ③Based on the results of color Doppler ultrasound examinations, percutaneous angioplasty was performed in 5 cases, surgical reconstruction in one case, and rEadjustment of the puncture site in 20 cases. Repeated color Doppler ultrasound examinations were required every 1- 3 months in 30 cases. Conclusion Color Doppler ultrasound examinations found higher rates of complications in functional AVFs with target Kt/V value. Color Doppler ultrasound parameters were closely related to the blood flow in AVFs, indicating that color Doppler ultrasound examination is useful for monitor of AVF functions and management of AVFs in clinical practice.

Key words: Functional autogenous arteriovenous fistula, Color Doppler ultrasound examination, Fistula complication