Abstract: 【Abstract】Objective To investigate the guiding role of real- time dynamic body weight monitoring combined with non- invasive hemodynamic monitoring in nursing care of patients undergoing continuous blood purification (CBP) treatment. Methods A total of 100 patients treated with CBP and with noninvasive hemodynamic monitoring before and after the treatment were enrolled in this study. They were randomly divided into two groups. In control group (n=50 cases), body weight was measured before and after CBP; in experiment group (n=50 cases), body weight was measured every hour before, during and after CBP by using a weighing bed, and the deviations were corrected. The compliance rates of volume load and body weight and the incidence of complications were compared between the two groups. Results For volume status, thoracic fluid content (TFC) in males, TFC in females, central venous pressure (CVP) and mean arterial pressure (MAP) were significantly lower in the experiment group as compared those in the control group (t=4.938, 3.621, 4.292 and 5.539 respectively; P＜0.001); the compliance rate of body weight was higher (χ2= 4.001, P=0.046) and the incidence of complications was lower (χ2=4.496, P=0.036) in the experiment group as compared those in the control group. Conclusion The use of real-time dynamic weight detection combined with non-invasive hemodynamic monitoring during CBP can easily observe the patients’volume status, correct the deviation immediately, and adjust the ultrafiltration volume accurately, thus useful for the performance of CBP treatment and nursing protocols in critically ill patients.

Key words: Continuous blood purification, Real-time dynamic weight monitoring, Volume status, Complication