Abstract: 【Abstract】Vitamin D binding protein (DBP) is synthesized in liver and distributed in tissues and organs throughout the body. In recent years, it has been reported that DBP not only binds, dissolves and transports vitamin D and its metabolites in circulation, but also has immune regulation function independent of vitamin D transport, which is related to the transformation and development of inflammation and tumor. Therefore, we summarized the recent progresses in DBP research, in order to provide reference for further study in this field.

Key words: Vitamin D binding protein, Vitamin D transportation, Inflammation, Tumor