Abstract: 【Abstract】Object To explore the effects of family members participating in nursing in a blood purification center. Methods A total of 80 maintenance hemodialysis (MHD) patients treated in the Department of Blood Purification of Dandong Central Hospital in the period from January 1, 2018 to December 31, 2018 were randomly divided into control group (n=40) and observation group (n=40). Patients in control group were treated with routine care, and those in observation group were treated with the model of nursecentered care plus family members participating in nursing. Before and after the intervention, dialysis effect, renal function index, nutrition index, self-rating depression scale (SDS) score, self-rating anxiety scale (SAS) score, and kidney disease quality of life short form (KDQOL-SFTM) score were compared between the two groups. Results After 12 months of intervention, the compliance rates of urea clearance index (Kt/V) and urea reduction rate (URR) were significantly higher in observation group than in control group (χ2=42.105 and 56.597, P＜0.001); body mass index, online clearance monitoring (OCM) value, hemoglobin and albumin levels were significantly higher in observation group than in control group (t=25.043, 24.845, 41.337 and 32.714 respectively, P＜0.001); malnutrition inflammation score (MIS) was significantly lower in observation group than in control group (t=38.256, P＜0.001). After 6 and 12 months of intervention, SDS score and SAS score were significantly lower in observation group than in control group (t=11.469 and 9.224, P＜0.001, after 6 months of intervention; t=32.962 and 22.965, P＜0.001, after 12 months of intervention); KDQOL-SFTM scores were significantly higher in observation group than in control group (t=18.556 and 16.268 respectively, P<0.001). Conclusion The model of nursing-centered care plus family members actively participating in nursing can improve dialysis sufficiency, nutrition index, psychological status and quality of life of the MHD patients.

Key words: Nurse, Nursing model, Blood purification