Abstract: 【Abstract】The metabolic disorders and dialysis-related factors in maintenance hemodialysis(MHD) patients may result in dysfunction in all aspects of the respiratory process. Respiratory dysfunction reduces quality of life and increases the risk of poor prognosis in MHD patients. Pulmonary rehabilitation can improve patients' exercise endurance and reduce dyspnea. In this paper, we will discuss the pathophysiological mechanisms and rehabilitation treatment of respiratory dysfunction in MHD patients, aiming to provide new insights into the pathophysiology of respiratory dysfunction and improve clinical management of MHD patients.

Key words: Hemodialysis, Respiratory disorder, Respiratory muscle, Pulmonary rehabilitation, Exercise therapy