Chinese Journal of Blood Purification ›› 2022, Vol. 21 ›› Issue (09): 625-627.doi: 10.3969/j.issn.1671-4091.2022.09.001

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Calciphylaxis, calcific uremic arteriolopathy or others

ZUO Li   

  1. Department of Nephrology, Peking University Peoples Hospital, Beijing 100044, China
  • Received:2022-06-07 Revised:2022-06-14 Online:2022-09-12 Published:2022-09-06

Abstract: Calciphylaxis is often used by nephrologist to describe a kind of painful skin dry gangrene in
some uremic patients. The underlining mechanisms of the skin gangrene is attributed to arterial smooth muscle cells active transformation to osteoblast-like cells, and medium layer calcification, lumen thrombosis and obstruction followed. But when the word calciphylaxis created, it had nothing to do with arterial medium layer calcification. It then was renamed as calcific uremic arteriolopathy. But, calciphylaxis, with the above-mentioned meaning, can also occurred in patients without uremia; never the less, it can also be detected in larger arteries outside organs. It seems now that calcific uremic arteriolopathy is also not a proper name for this condition. Then, what is the proper name for this skin change with medium layer calcification as underlining
mechanism?

Key words: ">Calciphylaxis">;">Calcificuremicarteriolopathy">;">Chronickidneydisease">

CLC Number: