Abstract: To summarize the nursing experience of a patient with end-stage liver disease and renal insufficiency who underwent continuous renal replacement therapy (CRRT) during allogeneic liver transplantation. The nursing key points include operating the machine compliant with the aseptic requirements in operating room, adopting a nursing plan for pre-flushing with anticoagulant and treatment without anticoagulant, timely adjusting treatment parameters according to the changes of key monitoring indicators during anhepatic phase, and analyzing the type of alarms and establishing a procedure for preprocessing an alarm. The patient underwent a liver transplantation surgery for 7 hours, and the total treatment time for CRRT was 9 hours with a smooth disease course.

Key words: Liver transplantation surgery, Continuous renal replacement therapy, Nursing