Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2025, Vol. 24 ›› Issue (03): 222-225.doi: 10.3969/j.issn.1671-4091.2025.03.011

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Furosemide loading test: potential to predict the timing of renal replacement therapy in patients with acute kidney injury

ZHOU Jie-rong, HOU Qi-liang, WANG Sen, YUAN Zi-qian, GAO Xing-mei, LI Bin   

  1. The First Clinical Medical School, Lanzhou University, Lanzhou 730000, China; 2Department of Intensive Care Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China
  • Received:2024-07-16 Revised:2024-11-12 Online:2025-03-12 Published:2025-03-12
  • Contact: 兰州 兰州 730000，1兰州大学第一临床医学院 730000，2兰州大学第一医院重症医学科 E-mail:libzhr@lzu.edu.cn

Abstract: The medical community has never reached a consensus on when to initiate renal replacement therapy (RRT) in patients with acute kidney injury (AKI). In recent years, furosemide loading test (FST) has shown its predictive potential. Early initiation of RRT is desirable in FST-positive patients, while it can be delayed in negative patients. However, the application of FST still has limitations and needs to be optimized to improve its prediction accuracy. In the future, a better AKI prediction model can be constructed by combining other biomarkers and clinical indicators to provide comprehensive guidance for physicians.

Key words: Acute kidney injury, Renal replacement therapy, Furosemide loading test 

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