【Abstract】 Objective Sumarize the clinical manifestation,treatment and resolution of the post-traumatic acute kidney injury(AKI). Methods 21 post-traumatic acute kidney injury patients(19 male,2 female) aged 10 to 85 (mean:55.8cases of crush syndrome,all patients were check for blood routine,urine routine,serum electrolytes (Na+﹑K+﹑Cl-﹑Ca2+﹑P3+﹑HCO3-）, liver function,serum albumin,renal function,serum uric acid and arterial blood gas analysis. Results All patients had bony fracture and crush injury of various degree, the average hemoglobin, albumin, serum calcium and bicarbonate level of the patients were lower than normal,the average serum uric acid and phosphorus level were higher than normal,compared with patients without crash syndrome,patients with crash syndrome had elevated serum potassium, phosphorus and BUN level, the differences were statistically significant; 4 patients had decompression surgery,1 patient had amputation,1 patient had undergone hemodialysis (HD) and haemodiafiltration (HDF ), 5 patients had undergone continuous venous venous hemofiltration (CVVH).After treatment,12 patients had full recovery of their renal function,3 patients had partial recovery of renal function,4 patients had no recovery of renal function and been transferred to other facilities in other provinces to continue their treatment. 1 patient with no recovery of his renal function and continued his treatment in our hospital and 1 patient died. Conclusion The post-traumatic acute kidney injury after the earthquake is the sequel of various pathologic processes,early diagnose,timely and proper manage the local crush trauma and early initiating hemopurification is crucial for the success of the treatment.