Abstract:

Objective To study the changes of hemodialysis and blood glucose in uremic patients of diabetic nephropathy treated with dialysate with and without glucose. Methods Maintenance hemodialyis using dialysate containing 0 or 5.5mmol/L glucose was performed in 28 uremic cases due to diabetic nephropathy. Clinical manifestations and biochemistry examinations were observed before and after the dialysis. Blood glucose was determined before the dialysis, after 2 hours and the end of the dialysis. Results There were no significant differences in blood pressure, weight changes during the dialysis period, hemoglobin concentration, serum potassium, hemodialytic sufficiency, nutrition state and blood lipids between patients using dialysate containing 5.5mmol/L glucose and those using the fluid without glucose (P＞0.05). In the processes of dialysis, blood glucose decreased slowly and returned to their initial levels after 4 hours in the patients using 5.5mmol/L glucose in the dialysate. Conclusion Dialysis fluid containing 5.5mmol/L glucose does not alter the hemodialysis efficiency and is safe to uremic patients caused by diabetic nephropathy.

Key words: Uremia, Hemodialysis, Blood glucose