Abstract: Remnant cholesterol (RC) is the cholesterol component of triglyceride-rich lipoproteins, existing in the form of intermediate-density lipoprotein (IDL) and very low-density lipoprotein (vLDL) in the fasting state, and as chylomicron remnants in the non-fasting state. Currently, the primary method  to obtain RC content is through the calculation of RC=total cholesterol (TC) - high-density lipoprotein cholesterol (HDL-C) - low-density lipoprotein cholesterol (LDL-C). RC is a significant risk factor for cardiovascular diseases, while cardiovascular disease is the leading cause of death in patients with chronic kidney disease (CKD). This article reviews the characteristics of blood lipids and the relationship between RC level and cardiovascular complications in CKD patients under various disease conditions, aiming to provide new insights into early identification and precise intervention of cardiovascular complications in CKD patients.

Key words: Remnant cholesterol, Cardiovascular disease, Chronic kidney disease, Lipid-lowering the-rapy