Abstract: 【Abstract】 Objective To investigate the risk factors for cardiocerebral vascular diseases in peritoneal dialysis (PD) patients. Methods One hundred and sixty-three patients who initiated PD during Jan. 2002～Dec. 2006, in our department were recruited in this study and divided into three groups: group 1, without cardiocerebral vascular diseases; group 2, with cardiocerebral vascular diseases before PD; group 3, cardiocerebral vascular diseases developed in the course of PD. Patients’ body weight, hemoglobin, albumin, triglycerides, total cholesterol, lipoprotein A, high-sensitivity C-reactive protein, interventricular septum thickness (IVST), left ventricular posterior wall thickness (LVPWT), ejection fraction (EF), and their disease history of diabetes and hypertension were collected. Results In the 163 PD patients, cardiocerebral vascular diseases were found in 121 cases (74.2%), of whom 75 patients were in group 2 and 46 patients in group 3. Before the end of Mar. 2007, 28 patients died, of whom 11 patients (39.3%) died of cardiocerebral vascular diseases. Diabetes and hypertension were found more in group 2 and 3 than in group 1. Hemoglobin were (94.3+22.4)g/L, (86.2+20.8)g/L and (86.8+18.1)g/L in group 1, 2 and 3, respectively (P<0.05). Serum albumin were (30.6+6.5)g/L, (27.3+5.1)g/L and (27.0+5.3)g/L in group 1, 2 and 3, respectively (P<0.01). Logistic regression analysis showed that diabetes, older catheterization age and lower EF were the risk factors for cardiocerebral vascular diseases in PD patients. Conclusion Diabetes, older catheterization age and lower EF are the risk factors related to cardiocerebral vascular diseases in PD patients. Intervention of these risk factors will improve their survival rate.

Key words: Cardiocerebral vascular diseases, Risk factors