Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2024, Vol. 23 ›› Issue (04): 286-289.doi: 10.3969/j.issn.1671-4091.2024.04.010

Previous Articles     Next Articles

Effects of the active form vitamin D on metabolism and kidney cell function in patients with chronic kidney disease

GUO Zi-Yi, ZHANG Zi-yuan, FANG Jing-ai   

  1. The First Clinical Medical School of Shanxi Medical University, Taiyuan 030001, China; 2Department of Nephrology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China 
  • Received:2023-11-28 Revised:2024-01-23 Online:2024-04-12 Published:2024-04-12
  • Contact: 030001 太原，2山西医科大学第一医院肾内科 E-mail:ziye_402@163.com

Abstract: Vitamin D is a lipid-soluble steroid derivative. Insufficiency or deficiency of vitamin D in patients with chronic kidney disease (CKD) affects calcium-phosphorus homeostasis, parathyroid hormone (PTH) level and glucose and lipid metabolism, leading to the presence of a series of complications, lower quality of life and reduced survival rate in CKD patients. This article reviews the mechanism of vitamin D on metabolism and kidney cell function in CKD patients to provide bases for the prevention and treatment of CKD and its complications.

Key words: Vitamin D, Chronic kidney disease, Calcium-phosphorus homeostasis, Parathyroid hormone, Glucose and lipid metabolism

CLC Number: