Abstract: Currently, neutrophils to lymphocytes ratio(NLR)has been recognized as a new predictive biomarker, and is widely used as a prognostic indicator for cardiovascular diseases, renal diseases, autoimmune diseases and others because it is less traumatic, economic, simple, high sensitive and specific. Hemodialysis (HD) is one of the essential measures for critically ill and end-stage renal disease patients to prolong their lives, but many complications occur inevitably. Early identification and treatment of theses complications are required. Previous studies have found that NLR may have the abilities to recognize and predict HD-related complications. This review summarizes the research progress in NLR changes in HD-related complications, to provide a basis for clinicians to evaluate the presence and prognosis of HD-related complications.

Key words: Hemodialysis, Neutrophil to lymphocyte ratio, Complications, Research progress