Abstract: ［Objective］: To Explore risk factors for stroke in peritoneal dialysis patients in single dialysis center. ［Methods］: Clinical data of 122 peritoneal dialysis patients admitted from January 2005 to January 2012 in Shenzheng 2nd people’s hospital were collected and retrospectively analyzed. Totally 17 cases were confirmed with stroke (group A, n=17) and the other 115 patients were not (group B, n=105). Correlational analyses between stroke and age, peritoneal dialysis duration, KT/V, hypertension, diabetes, homocysteine concentration, serum CRP levels, serum uric acid concentration,BNP were conducted. ［Results］Stroke was found in 17 (13.9%) cases of the analysis group which included 13 males(76.5%) and 4 females (23.5%) , in which hemorrhagic stroke were confirmed in 3 cases and ischemic stroke in other 14 cases. 11 patients with stroke were found aged over 60 (64.7%), only 6 cases with stroke were less than 60 years old （35.3%）.The A group of patients with an average age of 63.5±10.7 years, The B group of patients with an average age of 52.7±14.9 years, The A group of patients older than The B group of patients (P<0.05). The level of serum CRP and homocysteine concentration in group A was significantly higher than that in group B (P<0.05). Serum uric acid concentration in group A （340.4±71.0umol/l） was significantly lower than that in group B （418.4±119.1umol/l）, (P=0.01). Multivariate unconditional logistic regression analysis showed that hypertension（P=0.026）, diabetes（P=0.022), high level of serum CRP（P=0.001), high BNP concentration（P=0.045) ,high homocysteine concentration（P=0.017) were independent risk factors for stroke in peritoneal dialysis patients. ［Conclusion］: The incidence of stroke in our peritoneal dialysis patients was 13.9%. Hypertension, diabetes, high serum CRP level, high homocysteine concentration were independent risk factors for stroke in peritoneal dialysis patients.

Key words: Peritoneal dialysis, Stroke, Retrospective study