Abstract: 【Abstract】Objective To observe the effect of a parathyroidectomy on nutritional status of uremic patients with secondary hyperparathyroidism. Methods 30 uremic patients with secondary hyperparathyroidism receiced a parathyroidectomy. Before and 1 year after parathyroidectomy, nutritional status of the patients were valuated with modified quantitive subjective global assessment(MQSGA), anthropometric indices including triceps skin fold(TSF) and mid arm circumference(MAC) were measured, mid arm muscle circumference (MAMC) were calculated according to its formula.The patients were prospectively studied the serum parathyroid(iPTH),phosphorus(P),the product of calcium and phosphorus(Ca×P),calcium(Ca),Alb,Hb,Hct, transferrin(TF) before and 1 year after parathyroidectomy. Results Serum levels of iPTH,phosphorus,Ca×P and calcium were lower at 1 year after treatment compared with that before parathyroidectomy (tiPTH=-8.78,P=0.000,tp=-4.704,P=0.000,tca×p=-5.771,P=0.000,tca=-3.990, P=0.001).At 1 year after parathyroidectomy, Hb(113.4±14.5 vs 107.2±12.0,P=0.028)、Hct(0.34±0.05vs0.31±0.04,P=0.017)、Alb(41.2±3.6 vs39.5±4.0, P=0.016)were increased. MQSGA score were lower (8.93±2.12 vs 11.1±4.31,t=-2.652,P=0.013),TSF(10.23±2.00vs9.38±2.06,t=2.257,P= 0.035)，MAMC(22.3±2.43vs21.4±2.63, t=2.536, P=0.020) were improved. Conclusion Parathyroidectomy could improve nutritional status of uremic patients with secondary hyperparathyroidism.

Key words: Uremia, Secondary hyperparathyroidism, Parathyroidectomy, nutrition