Abstract: 【Abstract】Objective：To investigate the prognostic value of ambulatory blood pressure monitoring (ABPM) on outcome of patients with maintenance hemodialysis. Methods：45 maintenance hemodialysis patients from March to July in 2010 in our hospital were recruited . The data on the demographic, serum biochemical parameters as well as ABPM results of these patients were collected. The patients were followed up until death or December 2013. The long-term survival rates and impact factors were analyzed. Univariate and multivariate analysis Cox regression proportional hazard model were used to analysis the risk factors. Results：Over an average follow-up of 3.5 years，9 patients died. 7 were died of cardiovascular and cerebrovascular disease. Adjusted multivariate analyses showed mean arterial pressure (MAP)，minimum value of diastolic blood pressure (DBP) at night，nighttime DBP variability and non-dipper blood pressure as well as age were independent risk factors for death (HR： 1.248，1.577，2.101，0.000，1.461，respectively). Conclusions：The elevated MAP, minimum value of DBP at night，nighttime DBP variability and the non-dipper blood pressure pattern obtained by ABPM might be of prognostic importance for patients with maintenance hemodialysis.

Key words: Hemodialysis, ambulatory blood pressure monitoring, death