Abstract: Objective To study the hemodialysis modality of low temperature combined with sodium profile (combined hemodialysis) for the prevention of hypotension during hemodilysis. Methods A total of 26 hypotension patients were treated with the sodium profile hemodialysis, low temperature hemodialysis, or combined hemodialysis for 8 sessions. They were then blindly changed to one of the other two hemodialysis modalities. Therefore, every patient underwent the 3 hemodialysis modalities each for 8 sessions. Body weight, blood pressure, renal function, plasma electrolytes, and symptoms were monitored in these patients.
Result The prevalence of dizziness, perspiration, nausea, vomiting, and muscle spasms was lower after combined hemodialysis than that after the other two hemodialysis modalities (χ2= 8.980, 11.16, and 7.10, respectively, P <0.05～0.01). Analysis of variance showed that changes of systolic and diastolic blood pressure were present after sodium profile hemodialysis and low temperature hemodialysis (F =10.240 ～26.640, P < 0.01), but only systolic pressure (F =2.080, P＞0.05) changed without diastolic pressure changes after combined hemodialysis. Systolic and diastolic pressure changed significantly after low temperature hemodialysis, as compared to the blood pressure changes after the other two hemodialysis modalities. Serum sodium increased slightly after sodium profile hemodialysis and combined hemodialysis. In contrast, serum sodium after low temperature hemodialysis was lower than that after combined hemodialysis (t=2.360, P＜0.05). Conclusion Low temperature combined with sodium profile hemodialysis has little influences on blood pressure during dialysis, and is therefore suitable for patients with hypotension during dialysis.

Key words: Low temperature combined with sodium profile modality, Prevention, Hemodialysis, Hypotension