Abstract: 【Abstract】Objective To analyze the characteristics of arterioveneous fistula (AVF) in maintenance hemodialysis (MHD) patients with diabetes and its relevant factors. Methods A total of 98 MHD patients including 36 diabetic and 62 non-diabetic patients were enrolled in this study. Information about the time of fistula
surgery, the potency of the fistula, and the period of fistula dysfunction were collected and analyzed. Results ①n the diabetic group, the survival time of arterioveneous fistula was 55.14±6.58 month, significantly shorter than that in non-diabetic group. ②IOne way analysis of variance showed that CRP was 11.75±1.21mg/L and 5.68±3.16mg/L (P＜0.05), and PLT was (207.00±10.28)×109/L and (176.20±8.78)×109/L (P＜0.05) in diabetic group and non-diabetic group, respectively. ③Vascular ultrasound examination showed that vessel diameter was 2.01±0.11mm in diabetic patients narrower than that in non-diabetic group (2.38±0.12mm). Vascular intima hyperplasia was more prominent in diabetic group. Conclusions The survival time of autologous AVF was relatively shorter in MHD patients with diabetes. Vascular endothelial hyperplasia, and higher CRP and PLT may relate to the shorter survival time of AVF in these patients.

Key words: diabetic nephropathy, maintenance hemodialysis, autogenous arteriovenous fistula, risk factors