Abstract: Objective To investigate the clinical characteristics and short-term prognosis of hospital-acquired acute kidney injury (AKI) in the elderly. Methods The clinical data of hospital-acquired AKI patients admitted in the Ninth People’s Hospital from January 2013 to September 2014 were collected, and the elderly patients with AKI were then identified. Their clinical characteristics and risk factors for mortality within 90 days were analyzed. Results A total of 368 hospital-acquired AKI patients were identified. Of all the elderly patients (n=201), the mortality within 90 days was 34.8%. Among the non-elderly patients, the mortality within
90 days was 33.5%. The main causes of death for elderly patients were ischemia and infection. Multivariate analysis performed by Cox model showed that platelet (HR=0.996, 95% CI 0.993～0.999, P=0.005), C-reactive protein (HR=1.011, 95% CI 1.006～1.015, P＜0.001), mean arterial blood pressure (HR=0.981, 95% CI 0.967～0.996, P=0.001), APACHE II score (HR=1.053, 95% CI 1.023～1.084, P＜0.001), AKI complication (HR=2.406, 95% CI 1.220～4.745, P=0.011) were the independent variables predicting survival within 90 days in elderly AKI patients. Conclusions Lower platelet, higher C- reactive protein, lower mean arterial blood pressure, higher APACHE II score, and AKI complications were the independent risk factors for shortterm prognosis in elderly AKI patients.

Key words: elderly, acute kidney injury, prognosis