Abstract: Objective To investigate the related factors of hypocalcemia after parathyroidectomy in maintenance dialysis patients. Methods Forty-five patients treated with parathyroidectomy in the period from April, 2010 to November, 2014 were retrospectively studied. Clinical data of the patients before and after the operation were collected. Multivariate regression was conducted to confirm the factors influencing postoperative hypocalcemia. Results Hypocalcemia presented in all cases (100%) after the operation, and 43 cases of them had to treat with intravenous calcium．Using the length of intravenous calcium as the degree of hypocalcemia, univariate reggression showed that age (β=-0.104, P=0.049), preoperative serum calcium (β=-9.923, P=0.018), preoperative alkaline phosphate (ALP) (β=0.003, P=0.010), and the ratio of (postoperative ALP-preoperative ALP)/preoperative ALP (β=2.015, P=0.028) were the factors affecting postoperative hypocalcemia. Conclusions Age, preoperative serum calcium, preoperative ALP and the ratio of (postoperative ALP-preoperative ALP)/preoperative ALP are the factors influencing the hypocalcemia after parathyroidectomy.

Key words: Maintenance dialysis, Hyperparathyroidism, Parathyroidectomy, Hypocalcemia