Abstract: With the increasing number of chronic kidney disease patients worldwidely, how to improve the quality of life of these patients becomes an important issue. Vitamin D intake and synthesis of 25(OH) vitamin D are reduced because of the less diet intake and outdoor activities in peritoneal dialysis (PD) patients. Previous data showed that serum 25(OH) vitamin D level less than 50ng/ml was found in 97% PD patients. Serum vitamin D level is related to chronic kidney disease - mineral and bone disorder (CKD-MBD), cardiovascular events, cognitive function, muscle strength, etc. Supplement of vitamin D can prevent PD-related peritonitis and peritoneal fibrosis through the stimulation of macrophages and regulation of immune functions. Serum calcium, phosphorus and iPTH should be monitored regularly to prevent hypercalcemia during the supplement of vitamin D and its related preparations. This review focuses on vitamin D level in PD patients and the effects of vitamin D preparations on PD patients.

Key words: Chronic kidney disease, Vitamin D, Peritoneal dialysis