Abstract: Although the advances of hemodialysis (HD) technology have been made in recent years, the incidence of intra-dialytic hypotension (IDH) is still as high as 20～30%. The incidence of IDH increases associated the prevalence of aged patients, hypertensive nephropathy and diabetic nephropathy in HD patients. In 2007, the European Best Practice Guidelines (EBPG) emphasized the compliance with the Kidney Disease Outcomes Quality Initiative (K/DOQI) guidelines, and proposed that the definition of IDH was the decrease of intra-dialysis systolic blood pressure to ≥20mmHg for more than 2 times as compared with the pre-dialysis blood pressure or the decrease of mean arterial pressure to ≥10mmHg, accompanied by clinical events requiring medical intervention. In a retrospective study in 2014, Stefansson et al. analyzed the medical records of 39, 497 HD patients between 2007 and 2008 in the United States Renal Data System (USRDS) and hemodialysis centers in order to determine prognosis of the patients, and found that IDH was associated with increased risks of cardiovascular disease morbidity and mortality in HD patients.

Key words: hemodialysis, hypotension