Abstract: Objective To study the effect of individual management based on the 5E rehabilitation program on peritoneal dialysis (PD)-related peritonitis in uremic patients undergoing PD. Methods A total of 110 PD patients were recruited and randomly divided into two groups: the control group (n=54) treated with routine care procedures and the experimental group (n=55) treated with individual management including encouragement, education, exercise, employment and evaluation (5E) in addition to the routine care procedures. After one year, peritonitis, PD operation behavior, and inflammation-related symptoms before and after the intervention were compared between the two groups. Results A total of 109 PD patients were enrolled in this study. The prevalence of peritonitis was lower in the experimental group than in the control group (t=3.939, P=0.037). PD operation behavior and inflammation-related symptoms were statistically insignificant (t=3.939, P=0.037 for PD operation behavior; χ2=0.019, P=0.889 for inflammation-related symptoms) before the intervention between the two groups, but were better in the experimental group than in the control group (χ2=5.928, P=0.013 for PD operation behavior; χ2=7.210, P=0.007 for inflammation- related symptoms). Conclusion The individual management based on the 5E rehabilitation program can reduce inflammation- related symptoms and PD-related peritonitis, and improve PD operation in PD patients.

Key words: 5E program, peritoneal dialysis, peritonitis, individual management