Abstract: 【Abstract】Objective To evaluate the psychological and cognitive functions and their influential factors in maintenance hemodialysis (MHD) patients. Methods A total of 113 MHD patients with regular hemodialysis for more than three months in Beijing Bo’ai Hospital of China Rehabilitation Research Center in the period from May 1, 2017 to May 1, 2018 were enrolled in this study. Psychological function was assessed by Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS), and cognitive function was assessed by Simple Mental State Assessment Scale (MMSE). Results For psychological function in MHD patients, the prevalence rate of anxiety was 8.6% (mild anxiety 5.2% and severe anxiety 3.4%); the prevalence of depression was 69% (mild depression 29.3%, moderate depression 21.6% and severe depression 18.1%). For cognitive function in MHD patients, the prevalence of cognitive dysfunction was 33.6%; cerebrovascular disease was an independent risk factor for cognitive impairment, and the risk of cognitive impairment increased
significantly in MHD patients with cerebrovascular disease (OR=3.092, 95% CI: 1.192~8.025, P=0.020). Conclusion MHD patients have a higher prevalence rate of psychological disorders and cognitive dysfunction at various degrees. Cerebrovascular disease is an independent risk factor for cognitive dysfunction.

Key words: Hemodialysis, Psychological function, Cognitive function