Abstract: 【Abstract】Peritoneal dialysis (PD) is a principal renal replacement therapy. Sufficient fluid removal is an important target of PD. Inadequate fluid removal can lead to volume overload, which may endanger live of the PD patients. However, volume overload is still very common in PD patients. Automated peritoneal dialysis (APD) is a new type of PD, which can achieve enough peritoneal ultrafiltration through frequent exchange and short dwells in night time, thus improving the prognosis of PD patients with volume overload. This paper is a systematic review focusing on the epidemiology of volume overload, the adverse effects of volume overload, and the application of APD in PD patients with volume overload.

Key words: Automated peritoneal dialysis, Volume overload