Abstract: 【Abstract】Ferroportin (Fpn) is currently the unique iron export transfer protein, playing an important role in controlling the absorption of iron in diet and the excretion of iron from macrophages and other cells. Iron is an indispensable element in the body, participating in hemoglobin synthesis. If the expression of Fpn is disturbed, iron metabolism disorder and many related diseases will inevitably occur, red blood cell production is decreased, and chronic kidney disease (CKD) anemia is aggravated. This article reviews the research progress in Fpn, an important protein in the regulation of iron metabolism, in renal anemia.

Key words: Ferroportin, Chronic kidney disease, Anemia, Iron metabolism