Abstract: 【Abstract】In recent years, regional citrate anticoagulation (RCA) has been used increasingly in intermittent hemodialysis due to its unique advantages for patients with high risk of bleeding or active bleeding. In this paper, we review and analyze the application of RCA in intermittent hemodialysis in China and foreign countries in recent years, so as to provide a reference for its popularization.

Key words: Local anticoagulation, Sodium citrate, Hemodialysis