Abstract: 【Abstract】Objective To observe the effect of multidisciplinary, integrative and cooperative exercise therapy in maintenance hemodialysis (MHD) patients. Methods A total of 80 MHD patients treated in Huzhou Traditional Chinese Medicine Hospital affiliated to Zhejiang Chinese Medical University in the period between January 2019 and June 2020 were recruited as the research subjects. They were divided into experimental group (n=40) and control group (n=40) based on the envelope method. Patients in the experiment group were treated with the multidisciplinary, integrative and cooperative exercise therapy, and those in the control group received routine exercise nursing. Clinical parameters after the intervention were compared between the two groups. Results After the intervention, the compliance rate of exercise therapy (χ2=20.313, P＜0.001) and the comprehensive quality of life questionnaire scores of social domain (t=23.994, P＜0.001), material domain (t=22.761, P＜0.001), psychological domain (t=23.451, P＜0.001), and somatic domain (t=21.745, P＜0.001) were significantly higher in the experiment group than in the control group. Conclusion The application of multidisciplinary, integrative and cooperative kinesitherapy in the field of exercise
nursing during MHD therapy can significantly improve the compliance rate of kinesitherapy and the quality of life in these patients.

Key words: Multidisciplinary, Cooperative, Exercise therapy, Maintenance hemodialysis