Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2021, Vol. 20 ›› Issue (08): 536-539.doi: 10.3969/j.issn.1671-4091.2021.08.008

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A cross-sectional study on the prevalence and risk factors of maintenance hemodialysis-associated sarcopenia

  

  1. 1Graduate School of Hebei North University, Zhangjiakou 075000, China;  2Department of Nephrology, Air Force Medical Center of PLA, Beijing 100142, China;  3Department of Nephrology, the Fourth Medical Center of Chinese PLA General Hospital, Beijing 100048, China;  4Department of Nephrology, the Sixth Medical Center of Chinese PLA General Hospital, Beijing 100142, China;  5Blood Purification Center, Beijing Rensheng Hospital,Beijing 102300,China;  6Athletic Department, Tsinghua University, Beijing 100084, China
  • Received:2021-04-29 Revised:2021-06-01 Online:2021-08-21 Published:2021-08-05

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Abstract: 【Abstract】Objective To study the prevalence and risk factors of maintenance hemodialysis (MHD)-associated sarcopenia. Methods A total of 359 MHD patients were enrolled in this study. Clinical data of the patients were collected. Muscle mass, strength and muscle function were tested. Subjects were divided into sarcopenia group and non-sarcopenia group, and the prevalence and risk factors of sarcopenia were then analyzed. Results The 359 MHD patients were divided into the sarcopenia group (n=83) and the non-sarcopenia group (n=276). The prevalence of MHD-associated sarcopenia in the patients was 23.1%. Multivariate logistic regression analysis showed that age (OR=1.962, 95% CI=1.264~3.044, P=0.003), malnutrition (OR=2.697,
95% CI=1.283~5.669, P=0.009) and depression (OR=1.707, 95% CI=1.116~2.611, P=0.014) were the independent risk factors for sarcopenia, and BMI (OR=0.040, 95% CI=0.015~0.108, P＜0.001) was a protective factor for sarcopenia. Conclusion The prevalence of MHD-associated sarcopenia was 23.1%. Age, malnutrition and depression were the independent risk factors for sarcopenia, and BMI was a protective factor for sarcopenia.

Key words: Maintenance hemodialysis, Sarcopenia, Prevalence, Risk factor

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