Abstract: 【Abstract】Heart disease and kidney disease are often co- existed and interacted each other clinically. The therapy focused on a single organ is inappropriate to treat the diseases with multiple organ interactions. The concept of cardiorenal syndrome is therefore proposed. In this syndrome, fluid overload and venous congestion are critical issues to be solved, and ultrafiltration may be the best strategy after unresponsiveness of intravenous diuretics.

Key words: Cardiorenal syndrome, Ultrafiltration, Fluid overload, Application