Abstract: 【Abstract】Objective To investigate the independent risk factors for poor prognosis of peritoneal dialysis-associated peritonitis (PDAP). Methods The data of peritoneal dialysis (PD) patients from February 2015 to January 2021 in our department were retrospectively analyzed. Results Among the 142 cases of PDAP in this study, 100 cases cured, 19 cases relapsed, and 23 cases withdrew the treatment (extubation/death). Logistic regression showed that white blood cell count (OR=1.195, P=0.024) and serum albumin (OR=0.878, P=0.019) were the independent influencing factors for withdrawal (extubation/death) from PD (P<0.05). Compared with the PDAP patients of negative bacterial culture, those of pathogenic cocci bacteria had a better prognosis (OR=0.113, P=0.051). Among the cured patients, the remission days were longer in those with delayed treatment (>48h) than in those with earlier treatment (<24h) (Z=17.849, P<0.001). Conclusion The white blood cell count and serum albumin are the independent influencing factors for technical failure in PDAP patients. Delayed treatment prolongs the disease course.

Key words: Peritoneal dialysis, Peritonitis, Influencing factors, Delayed treatment