Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2022, Vol. 21 ›› Issue (07): 521-524.doi: 10.3969/j.issn.1671-4091.2022.07.013

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Research progress in the relationship between uremic toxins and sarcopenia in chronic kidney disease patients

  

  1. Department of Nephrology, South District of Guang-An-Men Hospital, China Academy of Chinese Medical Sciences, Beijing 102600, China;  Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China;  Graduate School of
    China Academy of Chinese Medical Sciences, Beijing 100700, China;      Department of Nephrology, Guang-AnMen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
  • Received:2021-12-23 Revised:2022-03-29 Online:2022-07-12 Published:2022-07-12

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Abstract: Sarcopenia in chronic kidney disease patients is caused by many factors, of which one is the
uremic toxins, which distinguishes CKD sarcopenia from other sarcopenias. We have reviewed and analyzed
the literature about the effect of uremic toxins on sarcopenia in order to comprehend the pathogenesis of sarcopenia and to find out the references for the treatment strategies of sarcopenia in CKD patients. Here we summarized the recent progresses in the relationship between uremic toxins and CKD sarcopenia, in an attempt to
explore a meaningful research subject and a novel strategy for the treatment of CKD sarcopenia by removal of
uremic toxins.

Key words: Uremic toxin, Sarcopenia, Review

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