Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2023, Vol. 22 ›› Issue (1): 44-47.doi: 10.3969/j.issn.1671-4091.2023.01.010

Previous Articles     Next Articles

Novel factors involved in chronic kidney disease-mineral and bone disorder (CKD-MBD) 

GUO Xin, FANG Jing-ai, WANG Rui-hua, ZHANG Xiao-dong,  LIU Wen-yuan, CHANG Qin-tao   

  1. First Clinical College, Shanxi Medical University, Taiyuan 030001,China; 2Department of Nephrology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2022-06-06 Revised:2022-08-12 Online:2023-01-12 Published:2023-01-12
  • Contact: 030001 太原，2山西医科大学第一附属医院肾内科 E-mail:wrh6807@163.com

PDF

373

Abstract: Many biological factors are involved in the occurrence and development of chronic kidney disease-mineral and bone disorder (CKD-MBD). In addition to the classic parathyroid hormone (PTH)/vitamin D axis theory, recent studies have found that fibroblast growth factor 23, FGF23/Klotho, dentin matrix protein 1 (DMP1), secretory protein DicKKOPF-1 (DKK1) and sclerostin are also directly or indirectly involved in the progression of CKD-MBD. This paper reviews the latest research on these factors.

Key words: Chronic kidney disease-mineral and bone disorder; , Fibroblast growth factor 23/Klotho, DKK1, Sclerostin, Dentin matrix protein1

CLC Number: