Chinese Journal of Blood Purification

Chinese Journal of Blood Purification ›› 2023, Vol. 22 ›› Issue (02): 90-94.doi: 10.3969/j.issn.1671-4091.2023.02.003

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Associations between geriatric nutritional risk index and clinical characteristics in maintenance hemodialysis patients

WANG Wei, SHI Rui, LI Xiu-yong, BAI You-wei, LIU Zhi, LIANG Shao-qin, CHEN Lei, TANG Xiao-fei, LI Ji, GUO Yu-wen, YUAN Liang, WANG De-guang   

  1. 1Blood Purification Center, XuanCheng People’s Hospital, Xuancheng 242000, China; 2Department of Nephrology, The Second Hospital of Anhui Medical University, Hefei 230601, China; 3Blood Purification Center, Fuyang Second People’s Hospital, Fuyang 236029, China; 4Department of Nephrology, Luan People’s Hospital, Luan 237006, China; 5Department of Nephrology, The First Hospital of Anhui University of Science and Technology, Huainan 232007, China; 6Blood Purification Center, Bozhou People’s Hospital, Bozhou 236814, China; 7Blood Purification Center, Hefei Jinnan Specialist Hospital for Nephrology, Hefei 230071, China; 8Blood Purification Center, Maanshan People’s Hospital, Maanshan 243099, China; 9Blood Purification Center, TongLing People’s Hospital, Tongling 244099, China; 10Department of Nephrology, Lujiang People’s Hospital, Hefei 231501, China
  • Received:2022-07-14 Revised:2022-11-23 Online:2023-02-12 Published:2023-02-12
  • Contact: 230601 合肥，2安徽医科大学第二附属医院肾内科 E-mail:wangdeguang@ahmu.edu.cn

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Abstract: Objective To evaluate the associated between Geriatric Nutritional Risk Index (GNRI) and clinical characteristics in maintenance hemodialysis (MHD) patients.  Methods  Two thousand six hundred and seventy-eight patients in MHD were recruited. Clinical characteristics of the patients were collected. We divided patients into the highest GNRI group (>98), considered to have no risk of malnutrition, the high GNRI group (92≤GNRI≤98), considered to have a low risk of malnutrition, median GNRI group (82≤GNRI＜92), considered to have a median risk of malnutrition, and low GNRI group (＜82), considered to have a high risk of malnutrition. Pearson correlation analyses and multiple linear regression analyses were conducted.  Results  One thousand and eighty-four patients (40.3%) were at risk of malnutrition. Pearson analysis showed that age (r=-0.101, P＜0.001) and hypersensitive c reactive protein (hsCRP) (r=-0.195, P=0.002) were negatively correlated with GNRI. Hemoglobin (r=0.266, P＜0.001), serum creatinine (r=0.225, P＜0.001),  triglyceride (r=0.147, P＜0.001), low density lipoprotein (r=0.089, P＜0.001), cholesterol (r=0.060, P=0.002), serum magnesium (r=0.113, P＜0.001), serum phosphorus (r=0.127, P＜0.001), parathyroid hormone (r=0.051, P=0.008) were positively correlated with GNRI. Multivariate logistic regression analysis shown that serum creatinine (β=0.070, P＜0.001), triglyceride (β=0.070, P＜0.001) and low density lipoprotein (β=0.034, P=0.009) were significantly associated with GNRI.  Conclusions  GNRI may be a reasonable indicator for assessment and monitoring of nutritional status in MHD patients. 

Key words: Geriatric nutritional risk index, Hemodialysis, Malnutrition

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